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Danish premature birth rates during the COVID-19 lockdown.

Identifieur interne : 000085 ( Main/Exploration ); précédent : 000084; suivant : 000086

Danish premature birth rates during the COVID-19 lockdown.

Auteurs : Gitte Hedermann [Danemark] ; Paula Louise Hedley [Danemark] ; Marie B Kvad-Hansen [Danemark] ; Henrik Hjalgrim [Danemark] ; Klaus Rostgaard [Danemark] ; Porntiva Poorisrisak [Danemark] ; Morten Breindahl [Danemark] ; Mads Melbye [Danemark, États-Unis] ; David M. Hougaard [Danemark] ; Michael Christiansen [Danemark] ; Ulrik Lausten-Thomsen [Danemark]

Source :

RBID : pubmed:32788391

Descripteurs français

English descriptors

Abstract

To explore the impact of COVID-19 lockdown on premature birth rates in Denmark, a nationwide register-based prevalence proportion study was conducted on all 31 180 live singleton infants born in Denmark between 12 March and 14 April during 2015-2020.The distribution of gestational ages (GAs) was significantly different (p=0.004) during the lockdown period compared with the previous 5 years and was driven by a significantly lower rate of extremely premature children during the lockdown compared with the corresponding mean rate for the same dates in the previous years (OR 0.09, 95% CI 0.01 to 0.40, p<0.001). No significant difference between the lockdown and previous years was found for other GA categories.The reasons for this decrease are unclear. However, the lockdown has provided a unique opportunity to examine possible factors related to prematurity. Identification of possible causal mechanisms might stimulate changes in clinical practice.

DOI: 10.1136/archdischild-2020-319990
PubMed: 32788391
PubMed Central: PMC7421710


Affiliations:


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Le document en format XML

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<title level="j">Archives of disease in childhood. Fetal and neonatal edition</title>
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<term>COVID-19 (epidemiology)</term>
<term>Denmark (epidemiology)</term>
<term>Humans (MeSH)</term>
<term>Infant, Extremely Premature (MeSH)</term>
<term>Infant, Newborn (MeSH)</term>
<term>Pandemics (MeSH)</term>
<term>Premature Birth (epidemiology)</term>
<term>Prevalence (MeSH)</term>
<term>SARS-CoV-2 (MeSH)</term>
<term>Social Isolation (MeSH)</term>
</keywords>
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<term>Danemark (épidémiologie)</term>
<term>Humains (MeSH)</term>
<term>Isolement social (MeSH)</term>
<term>Naissance prématurée (épidémiologie)</term>
<term>Nouveau-né (MeSH)</term>
<term>Pandémies (MeSH)</term>
<term>Prévalence (MeSH)</term>
<term>Très grand prématuré (MeSH)</term>
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<term>Denmark</term>
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<term>Infant, Newborn</term>
<term>Pandemics</term>
<term>Prevalence</term>
<term>SARS-CoV-2</term>
<term>Social Isolation</term>
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<keywords scheme="MESH" xml:lang="fr">
<term>Humains</term>
<term>Isolement social</term>
<term>Nouveau-né</term>
<term>Pandémies</term>
<term>Prévalence</term>
<term>Très grand prématuré</term>
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<term>Danemark</term>
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<div type="abstract" xml:lang="en">To explore the impact of COVID-19 lockdown on premature birth rates in Denmark, a nationwide register-based prevalence proportion study was conducted on all 31 180 live singleton infants born in Denmark between 12 March and 14 April during 2015-2020.The distribution of gestational ages (GAs) was significantly different (p=0.004) during the lockdown period compared with the previous 5 years and was driven by a significantly lower rate of extremely premature children during the lockdown compared with the corresponding mean rate for the same dates in the previous years (OR 0.09, 95% CI 0.01 to 0.40, p<0.001). No significant difference between the lockdown and previous years was found for other GA categories.The reasons for this decrease are unclear. However, the lockdown has provided a unique opportunity to examine possible factors related to prematurity. Identification of possible causal mechanisms might stimulate changes in clinical practice.</div>
</front>
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<Year>2020</Year>
<Month>12</Month>
<Day>22</Day>
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<DateRevised>
<Year>2021</Year>
<Month>01</Month>
<Day>10</Day>
</DateRevised>
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<Journal>
<ISSN IssnType="Electronic">1468-2052</ISSN>
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<Volume>106</Volume>
<Issue>1</Issue>
<PubDate>
<Year>2021</Year>
<Month>Jan</Month>
</PubDate>
</JournalIssue>
<Title>Archives of disease in childhood. Fetal and neonatal edition</Title>
<ISOAbbreviation>Arch Dis Child Fetal Neonatal Ed</ISOAbbreviation>
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<ArticleTitle>Danish premature birth rates during the COVID-19 lockdown.</ArticleTitle>
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<MedlinePgn>93-95</MedlinePgn>
</Pagination>
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<AbstractText>To explore the impact of COVID-19 lockdown on premature birth rates in Denmark, a nationwide register-based prevalence proportion study was conducted on all 31 180 live singleton infants born in Denmark between 12 March and 14 April during 2015-2020.The distribution of gestational ages (GAs) was significantly different (p=0.004) during the lockdown period compared with the previous 5 years and was driven by a significantly lower rate of extremely premature children during the lockdown compared with the corresponding mean rate for the same dates in the previous years (OR 0.09, 95% CI 0.01 to 0.40, p<0.001). No significant difference between the lockdown and previous years was found for other GA categories.The reasons for this decrease are unclear. However, the lockdown has provided a unique opportunity to examine possible factors related to prematurity. Identification of possible causal mechanisms might stimulate changes in clinical practice.</AbstractText>
<CopyrightInformation>© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.</CopyrightInformation>
</Abstract>
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<LastName>Hedermann</LastName>
<ForeName>Gitte</ForeName>
<Initials>G</Initials>
<Identifier Source="ORCID">http://orcid.org/0000-0001-8853-0986</Identifier>
<AffiliationInfo>
<Affiliation>Department for Congenital Disorders, Danish National Biobank and Biomarkers, Statens Serum Institut, Copenhagen, Denmark.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Hedley</LastName>
<ForeName>Paula Louise</ForeName>
<Initials>PL</Initials>
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<Affiliation>Department for Congenital Disorders, Danish National Biobank and Biomarkers, Statens Serum Institut, Copenhagen, Denmark.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Bækvad-Hansen</LastName>
<ForeName>Marie</ForeName>
<Initials>M</Initials>
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<Affiliation>Department for Congenital Disorders, Danish National Biobank and Biomarkers, Statens Serum Institut, Copenhagen, Denmark.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Danish Center for Neonatal Screening, Statens Serum Institut, Copenhagen, Denmark.</Affiliation>
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<LastName>Hjalgrim</LastName>
<ForeName>Henrik</ForeName>
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<Affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Department of Haematology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.</Affiliation>
</AffiliationInfo>
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<LastName>Rostgaard</LastName>
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<ForeName>Morten</ForeName>
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</Author>
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<LastName>Melbye</LastName>
<ForeName>Mads</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Department of Medicine, Stanford University School of Medicine, Stanford, CA, US.</Affiliation>
</AffiliationInfo>
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</AffiliationInfo>
<AffiliationInfo>
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</AffiliationInfo>
</Author>
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<ForeName>Ulrik</ForeName>
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<AffiliationInfo>
<Affiliation>Department of Neonatology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark mic@ssi.dk ulrik.lausten-thomsen@regionh.dk.</Affiliation>
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<KeywordList Owner="NOTNLM">
<Keyword MajorTopicYN="N">epidemiology</Keyword>
<Keyword MajorTopicYN="N">neonatology</Keyword>
</KeywordList>
<CoiStatement>Competing interests: MB has a patent (NeoHelp) with royalties paid.</CoiStatement>
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